Dr. Geraldine Hartshorne, PhD

Dr. Geraldine HartshorneProfessor Geraldine Hartshorne is Head of Research Degree Studies of the Warwick Medical School at the University of Warwick, UK, and Scientific Director of the Centre for Reproductive Medicine, University Hospitals Coventry and Warwickshire NHS Trust.

Her research career began in Cambridge, with a PhD supervised by Professor Robert Edwards, who not only stimulated her scientific research but also engaged her in a broad range of clinical, editorial, educational and ethical activities that form the foundations of her current portfolio. She won the McIlrath Research Fellowship at St Hilda’s College and initiated a seminal study of early meiosis in human females. In 1995, she moved to the University of Warwick, to lead scientific services at the Centre for Reproductive Medicine, as a Principal Research Fellow in Biological Sciences.

Her research on indicators of human oocyte and embryo development, licensed by the Human Fertilisation and Embryology Authority, studies both basic scientific and clinical quality assessments, turning most recently towards implantation signalling.

Dr. Hartshorne is also a pathologist for clinical embryologists and she supervises PhD and MD students within the Biomedical Research Unit in Reproductive Health.

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Dr. Frederick W. K. Kan, PhD

Dr. Frederick KanDr. Frederick W. K. Kan is professor of anatomy and cell biology in the Department of Biomedical and Molecular Sciences of the Faculty of Health Sciences at Queen’s University. His research career began at McGill University in Montreal where he completed both his M.Sc. and Ph.D degrees under the mentorship of the late Professor Charles Philippe Leblond whose dynamic personality as a pioneer in cell biology and stem cell research motivated him to pursue a career in research and academia.

After completing post-doctoral training at the National Institutes of Health in the U.S., he was appointed an assistant professor in the Department of Anatomy and Cell Biology of the Faculty of Medicine at the University of Montreal. He was a scholar from the Medical Research Council (MRC) of Canada which is now known as the Canadian Institutes of Health Research (CIHR). At the University of Montreal, Professor Kan developed a research interest in studying the role of oviductal secretions in regulation of gamete interaction and fertilization and became one of the pioneers in investigating the role of an oviduct-specific glycoprotein also known as oviductin in reproductive function.

In 1994, he moved to Queen’s University and continued his research in studying the role of human oviductin in the early events of fertilization. He was the acting head of the Department of Anatomy and Cell Biology from 2001-2002 and designated director of the Research Group in Reproduction, Development and Sexual Function from 2002-2004. Professor Kan is actively engaged himself in teaching undergraduate students and supervising graduate students and research trainees. His research program has been supported by the Canadian Institutes of Health Research (CIHR) and the Natural Science and Engineering Research Council of Canada (NSERC). He has also served as a member of several grant review panels for CIHR and as a member of a grant review committee for NSERC.

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Dr. José A. Horcajadas, PhD

Dr. Jose HorcajadasDr. Horcajadas is a researcher at Aragon I+D, Assistant Professor at the University Pablo de Olavide, Sevilla, Spain and Chief Scientific Officer, Recombine EU, Bilbao, Spain. He has previously held positions as Chief Scientific Officer at Reprogenetics Argentina and Mexico, Chief Scientific Officer at iGLS, Alicante, Spain and Adjunt Research Associate Professor at EVMS, Norfolk, VA.

Dr. Horcajadas graduated in Biology (Speciality of Molecular Biology and Biochemistry) from the Universidad Autónoma of Madrid in 1993. He was a Predoctoral Fellow of the Madrid Community in the Institute of Biomedical Research of Madrid and Center of Molecular Biology “Severo Ochoa” until 2000. He was also awarded a Postdoctoral fellowship from Foundation Raúl González-Salas for one year in the same center.

His research has focused on the molecular basis of embryonic implantation and endometrial receptivity, and was principal researcher of a Grant from Generalitat Valenciana for young scientists in 2004 and 2005. He has also been principal researcher on other projects funded by pharmaceutical companies (Ferring) and private foundations (Bertarelli Foundation) and won the prize Salud 2000 in 2004 for a study in the field of obesity and infertility and at 2012 at American Society of Reproductive Medicine.

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Dr. Teruko Taketo, PhD

Dr. Teruko TaketoDr. Taketo holds a PhD. in Pharmacology from Kyoto University, Japan. Her postdoctoral training was conducted at the Biomedical Research Center, Population Council, New York and is currently an Associate Professor in the Department of Surgery, McGill University. Her work is supported by CIHR, NSERC, and MITACS grants.

Dr. Taketo’s research interests are primarily focused on women’s fertility. As she explains, women’s fertility is limited by the quantity and quality of eggs (named oocytes), both of which decline with maternal ageing. She has published research on (1) the mechanism that determines how many and which oocytes are retained during fetal development, and (2) how bidirectional communications between an oocyte and its surrounding follicular cells influence oocyte competence for embryonic development.

Additionally, Dr. Taketo is also interested in a surveillance mechanism by which errors in chromosome processing result in elimination of oocyte and sperm progenitors. Her laboratory uses mouse fertility models to investigate these questions to further understand the essential mechanisms that control oocyte and embryo quality and help improve assisted reproductive technology outcomes for infertile couples.

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Dr. Benjamin K. Tsang, PhD

Dr. Benjamin TsangDr. Tsang is the Director of the Ottawa Hospital Research Institute’s Reproductive Biology Unit. He is also a Professor of Obstetrics & Gynaecology and Cellular & Molecular Medicine at the Interdisciplinary School of Health Sciences at the University of Ottawa and a Senior Scientist with the Chronic Disease Program at the Ottawa Hospital Research Institute.

Among his many accomplishments, Dr. Tsang has participated in several major research programs directly related to our core mission including mechanisms of chemoresistance in ovarian cancer (OVCA), ovarian follicular growth and female infertility. The overall goal of the OVCA program is to better understand the mechanisms of chemoresistance in OVCA with possible involvement of p53, gelsolin (GSN) and Akt in the control of mitochondrial fission and fusion and nuclear function. The program integrates in vitro, in vivo, and clinical approaches in dissecting the mechanisms of chemoresistance in OVCA. The studies will provide novel insights in the pathobiology of chemoresistance and new therapeutic strategies.

The ovarian follicular growth and female infertility research program is focused primarily on (1) defining the physiologic actions and interactions of endocrine and intra-ovarian regulators and their intracellular signaling pathways and mechanisms in the control of normal follicular growth; and (2) understanding the complex pathophysiology of polycystic ovarian syndrome (PCOS)

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